ミトコンドリアＤＮＡと染色体（遺伝子） ― 2009/10/16 14:59
人類の起源を探るのに、分子人類学が大きな役割を果たしているということは、これまでに紹介した文献などから、よく分かると思います。
ここで登場するのは、ミトコンドリアＤＮＡや、Ｙ染色体で、母系または父系に遺伝し、人類がどこから来て、どのように世界各地へ拡散していったのかを紐解くのに、大いに役に立ちます。
あらたまった事を書くようですが、日本人の起源についても、分子人類学は多くのことを推測することができ、日本人には多くのハプログループが存在することから、時代も場所も異なる多くの所から人々が集まったと考えられています。（『新・日本人の起源』（崎谷 満：勉誠出版）より。以下、文献①と略）
さて、ミトコンドリアＤＮＡにしろ、Ｙ染色体にしろ、多くのハプログループが混在している日本人には、多様な遺伝子が混在している、と考えることができます。
しかし、そんなに単純に考えられるのでしょうか？
文献①では、「人種」というものの概念が無意味であるとのことから、Ｙ染色体ハプログループの分布と、「人種」との関係を挙げています。
そこでは、例えばマクロハプログループＤＥには、コーカソイドにモンゴロイド、ネグロイドまで存在します。マクロハプログループＣについても、地域は異なるものの、いわゆる人種（肌の色）という形では、さまざまな人種が存在します。
文献①の著者いわく、人種は異なっていてもマクロハプログループは同じであり、また、人種は同じでも、マクロハプログループが異なることがあるので、肌の色による人種の分類が、科学的な根拠が無い、ということです。
「遺伝」や「遺伝子」という事に詳しい人なら、混同することもないのでしょうが、私自身、ちょっとした勘違いをしていたかもしれません。
まず、ハプログループが同じであれば、似ている近い人達なのではないか、ということ。
例えば、日本人に存在するミトコンドリアＤＮＡのハプログループＭ７ａは、シベリア南部～極東あたりが起源と考えられています。（文献①）
すると、素人考えでは、シベリア南部辺りの人達と、どこか少しでも似たところを持つ日本人が、ほんの少しはどこかに居るのだろう、と。
これは、全くの的外れではないのかもしれませんが、本質的なことはまた別のところにあるような気がします。
うまく説明できないので、試しに次のようなケースを考えてみます。（「人種」を挙げていますが、差別的な意味合いはありません。また、mDNAはミトコンドリアＤＮＡの事です。）
① ♂黒人 － ♀白人（mDNA-M7a）
② ①夫婦の娘：♀肌の色は不明（mDNA-M7a) － ♂黒人（夫）
③ ②夫婦の娘：♀肌の色は黒に近い？（mDNA-M7a) － ♂黒人(夫）
④ ③夫婦の娘：♀肌の色は黒に近い？(mDNA-M7a)
ちょっと極端な例だとは思いますが、元々白人女性(mDNA-M7a)の子、孫、ひ孫と女系であれば、ミトコンドリアＤＮＡは受け継がれますが、相手が黒人であれば、染色体の遺伝子の影響で、段々と肌の黒い子が誕生するハズです。
分かっている人にとっては当たり前の事ですが、ミトコンドリアＤＮＡや、Ｙ染色体のハプログループと、肌の色を始めとする形質的な遺伝は関係がありません。それは、上記の人種とハプログループの関係からも明らかです。
さて、何が言いたいのかよく分からなくなってきました。
ｍＤＮＡや、Ｙ染色体のハプログループを遡って、どうなるのだろう？
もちろん、それがアフリカを起源とする人類発祥の地を突き止めた異議は大きいでしょう。しかし、その途中はどうなのか？
変な例えですが、私は一応父親で、娘がいます。
私のｍＤＮＡは、娘へは受け継がれていません。もちろん、偶然同じ可能性はあります。
そして、娘なので、Ｙ染色体も娘へは受け継がれていません。
恐らく、どこかそんなに遠くないところにも、私と同じｍＤＮＡや、Ｙ染色体を持つ子供たちが居るでしょう。（判別はできませんが・・・。）
だからと言って、自分の娘より、その子供たちをかわいがる訳ではありません。
ｍＤＮＡも、Ｙ染色体も受け継がれていませんが、その他の染色体（遺伝子）の５０％は、受け継いでいるはずです。
なんだか、話しが脱線しているようなので、今日はここまでにしておきます。（なんとなく、まとまるような気はしませんが・・・。）
ここで登場するのは、ミトコンドリアＤＮＡや、Ｙ染色体で、母系または父系に遺伝し、人類がどこから来て、どのように世界各地へ拡散していったのかを紐解くのに、大いに役に立ちます。
あらたまった事を書くようですが、日本人の起源についても、分子人類学は多くのことを推測することができ、日本人には多くのハプログループが存在することから、時代も場所も異なる多くの所から人々が集まったと考えられています。（『新・日本人の起源』（崎谷 満：勉誠出版）より。以下、文献①と略）
さて、ミトコンドリアＤＮＡにしろ、Ｙ染色体にしろ、多くのハプログループが混在している日本人には、多様な遺伝子が混在している、と考えることができます。
しかし、そんなに単純に考えられるのでしょうか？
文献①では、「人種」というものの概念が無意味であるとのことから、Ｙ染色体ハプログループの分布と、「人種」との関係を挙げています。
そこでは、例えばマクロハプログループＤＥには、コーカソイドにモンゴロイド、ネグロイドまで存在します。マクロハプログループＣについても、地域は異なるものの、いわゆる人種（肌の色）という形では、さまざまな人種が存在します。
文献①の著者いわく、人種は異なっていてもマクロハプログループは同じであり、また、人種は同じでも、マクロハプログループが異なることがあるので、肌の色による人種の分類が、科学的な根拠が無い、ということです。
「遺伝」や「遺伝子」という事に詳しい人なら、混同することもないのでしょうが、私自身、ちょっとした勘違いをしていたかもしれません。
まず、ハプログループが同じであれば、似ている近い人達なのではないか、ということ。
例えば、日本人に存在するミトコンドリアＤＮＡのハプログループＭ７ａは、シベリア南部～極東あたりが起源と考えられています。（文献①）
すると、素人考えでは、シベリア南部辺りの人達と、どこか少しでも似たところを持つ日本人が、ほんの少しはどこかに居るのだろう、と。
これは、全くの的外れではないのかもしれませんが、本質的なことはまた別のところにあるような気がします。
うまく説明できないので、試しに次のようなケースを考えてみます。（「人種」を挙げていますが、差別的な意味合いはありません。また、mDNAはミトコンドリアＤＮＡの事です。）
① ♂黒人 － ♀白人（mDNA-M7a）
② ①夫婦の娘：♀肌の色は不明（mDNA-M7a) － ♂黒人（夫）
③ ②夫婦の娘：♀肌の色は黒に近い？（mDNA-M7a) － ♂黒人(夫）
④ ③夫婦の娘：♀肌の色は黒に近い？(mDNA-M7a)
ちょっと極端な例だとは思いますが、元々白人女性(mDNA-M7a)の子、孫、ひ孫と女系であれば、ミトコンドリアＤＮＡは受け継がれますが、相手が黒人であれば、染色体の遺伝子の影響で、段々と肌の黒い子が誕生するハズです。
分かっている人にとっては当たり前の事ですが、ミトコンドリアＤＮＡや、Ｙ染色体のハプログループと、肌の色を始めとする形質的な遺伝は関係がありません。それは、上記の人種とハプログループの関係からも明らかです。
さて、何が言いたいのかよく分からなくなってきました。
ｍＤＮＡや、Ｙ染色体のハプログループを遡って、どうなるのだろう？
もちろん、それがアフリカを起源とする人類発祥の地を突き止めた異議は大きいでしょう。しかし、その途中はどうなのか？
変な例えですが、私は一応父親で、娘がいます。
私のｍＤＮＡは、娘へは受け継がれていません。もちろん、偶然同じ可能性はあります。
そして、娘なので、Ｙ染色体も娘へは受け継がれていません。
恐らく、どこかそんなに遠くないところにも、私と同じｍＤＮＡや、Ｙ染色体を持つ子供たちが居るでしょう。（判別はできませんが・・・。）
だからと言って、自分の娘より、その子供たちをかわいがる訳ではありません。
ｍＤＮＡも、Ｙ染色体も受け継がれていませんが、その他の染色体（遺伝子）の５０％は、受け継いでいるはずです。
なんだか、話しが脱線しているようなので、今日はここまでにしておきます。（なんとなく、まとまるような気はしませんが・・・。）
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I'm curious to find out what blog system you happen to be working with?
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I'm extremely impressed with your writing skills and also with the layout on your blog.
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I'm really inspired with your writing talents as neatly as with the structure in your weblog.
Is that this a paid subject or did you customize it your self?
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I must say you have done a fantastic job with this.
Additionally, the blog loads super fast for me on Internet explorer.
Superb Blog!|
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Howdy would you mind sharing which blog platform you're
working with? I'm looking to start my own blog in the near future but I'm having a tough time making a decision between BlogEngine/Wordpress/B2evolution and Drupal.
The reason I ask is because your design and style
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P.S My apologies for being off-topic but I had to ask!|
Hey would you mind letting me know which web host you're using?
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Greetings! Very helpful advice within this article!
It is the little changes which will make the most
important changes. Thanks for sharing!|
I seriously love your blog.. Very nice colors & theme. Did
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I've been using WordPress on numerous websites for about a year and am
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heard great things about blogengine.net. Is there a way
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I'm curious to find out what blog system you're working with?
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I am extremely impressed with your writing skills and also with the layout
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I am really inspired with your writing abilities as smartly as with the layout to your weblog.
Is this a paid topic or did you modify it your self?
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I never found any interesting article like yours.
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much more useful than ever before.|
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I'll right away snatch your rss feed as I can not
find your email subscription link or newsletter service.
Do you have any? Please permit me realize in order that
I may just subscribe. Thanks.|
It is appropriate time to make some plans for the future and it is time to be happy.
I have read this post and if I could I want to suggest you some interesting things or suggestions.
Perhaps you can write next articles referring to this article.
I desire to read more things about it!|
It is the best time to make some plans for the longer term
and it's time to be happy. I have learn this
post and if I may just I wish to counsel you few interesting issues or suggestions.
Perhaps you can write subsequent articles referring to this article.
I desire to learn more issues about it!|
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yours. It's pretty value enough for me. In my opinion, if all webmasters and
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of things, so I am going to inform her.|
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Way cool! Some very valid points! I appreciate you writing this write-up plus the rest of the website is really good.|
Hi, I do believe this is an excellent blog.
I stumbledupon it ;) I may return once again since i have book marked it.
Money and freedom is the best way to change, may you be rich
and continue to help other people.|
Woah! I'm really enjoying the template/theme of this site.
It's simple, yet effective. A lot of times it's tough to get that "perfect balance" between superb usability and visual appearance.
I must say you have done a fantastic job with this.
Additionally, the blog loads super fast for me on Internet explorer.
Superb Blog!|
These are really great ideas in on the topic of blogging.
You have touched some pleasant points here.
Any way keep up wrinting.|
I love what you guys are up too. This kind of clever work and reporting!
Keep up the excellent works guys I've incorporated you guys to our blogroll.|
Hi there! Someone in my Facebook group shared this website with
us so I came to take a look. I'm definitely enjoying the information. I'm book-marking
and will be tweeting this to my followers! Great blog and great design and style.|
Everyone loves what you guys are usually up too. This kind of clever work and exposure!
Keep up the superb works guys I've included you guys to
my personal blogroll.|
Howdy would you mind sharing which blog platform you're
working with? I'm looking to start my own blog in the near future but I'm having a tough time making a decision between BlogEngine/Wordpress/B2evolution and Drupal.
The reason I ask is because your design and style
seems different then most blogs and I'm looking for something completely unique.
P.S My apologies for being off-topic but I had to ask!|
Hey would you mind letting me know which web host you're using?
I've loaded your blog in 3 completely different internet
browsers and I must say this blog loads a lot faster then most.
Can you recommend a good hosting provider at a honest price?
Thanks, I appreciate it!|
Everyone loves it whenever people get together and share thoughts.
Great website, continue the good work!|
Thank you for the auspicious writeup. It in fact was a
amusement account it. Look advanced to far added agreeable from you!
However, how could we communicate?|
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